The exclusive gathering for AI founders, researchers, and leaders building at the forefront of the industry and driving the AI strategies, agendas, and products of tomorrow.

Sept 30 - Oct 1, 2025
Four Seasons, Seattle
Check out the just-announced
2023 IA40 Winners

Featured Speakers

Intelligent and generative applications are defining the next generation of innovation. New GenAI, agentic, and infrastructure stacks are emerging. At the 2025 IA Summit we'll hear from founders at the cutting edge and established companies building for the future.

Yann Lecun
Jason Kwon
Chief Strategy Officer
Daphne Koller
Carina Hong
Founder & CEO
Summit Chauhan
Eric Simons
CEO
Marco Argenti
Anu Bharadwaj
President

Join top researchers, investors, and builders to explore the challenges and opportunities in creating next-generation intelligent applications and companies. From cutting-edge frontier models to the fastest-growing and largest companies at the application layer, the IA Summit is a curated gathering of leaders driving the AI strategies, agendas, and products of tomorrow.

AI Podcasts

2025 IA Summit Agenda

Sept. 30
5-7 p.m.
Welcome Reception
Oct. 1
8:30 a.m.
Registration & Breakfast
9 a.m.
Welcome & Opening Remarks
9:20 a.m.
Fireside Chat: Reasoning Machines Everywhere — From Data Centers to Distribution Centers
Rohit Prasad, SVP & Head Scientist for Artificial General Intelligence, Amazon
Matt McIlwain, Managing Director, Madrona
9:45 a.m.
Fireside Chat: How the Data Layer Supports Reasoning Machines
Nikita Shamgunov, Vice President, Databricks
Parag Agarwal, Founder & CEO, Parallel
Moderated by Jon Turow, Partner, Madrona
10:10 a.m.
IA40 Winner Spotlights
Modal — CEO Erik Bernhardsson
Browserbase — Founder & CEO Paul Klein
Aaru — Co-founder Ned Koh
10:45 a.m.
Break
11 a.m.
Panel: Enterprise Reasoning and AI Adoption
Eric Phillips, Senior Vice President & Chief Digital Officer, Delta Airlines
Arvind Jain, CEO, Glean
Marco Argenti, Chief Information Officer, Goldman Sachs
Moderated by Lari Hamalainen, Senior Partner, McKinsey & Company  
11:30 a.m.
Panel: Abstracting Infrastructure to Power Modern Models
Jonathan Cohen, Vice President of Applied Research, Nvidia
Noah Smith, Senior Director of NLP Research, AI2 & Professor of Computer Science & Engineering, UW
Vijay Karunamurthy, EIR, Khosla Ventures
Moderated by Dina Bass, Reporter, Bloomberg  
11:55 a.m.
Fireside Chat: The Evolution of Data Centers
Chase Lochmiller, Co-founder & CEO, Crusoe
Ben Gilbert, Co-founder & Co-host, Acquired Podcast
12:20 p.m.
Lunch & Networking
1 p.m.
Fireside Chat: The Collaborative Reasoning Full Stack
Jason Kwon, Chief Strategy Officer, OpenAI
Vivek Ramaswami, Partner, Madrona  
1:25 p.m.
Panel: Reasoning Machines — From Vibe Coding to Vibe-X’ing
Eric Simons, Co-founder & CEO, Stackblitz
Zeb Hermann, GM of v0, Vercel
Adam Sypniewski, CTO, Deepgram
Moderated by Nikita Shamgunov, Vice President, Databricks
1:50 p.m.
Panel: Reasoning Agentic Productivity
Anu Bharadwaj, President, Atlassian
Rob Seaman, Chief Product Officer, Slack at Salesforce
David Shim, Co-founder & CEO, Read AI
Moderated by Mark Nelson, Venture Partner, Madrona
2:20 p.m.
IA40 Winner Spotlights
Arjun Prakash, Co-founder & CEO, Distyl AI
2:40 p.m.
Break
2:55 p.m.
Fireside Chat: Reasoning Engines — The Next Frontier in AI
Carina Letong Hong, Founder & CEO, Axiom Math
Byron Cook, VP Distinguished Scientist, Amazon
Moderated by Jon Turow, Partner, Madrona
3:20 p.m.
IA40 WInner Spotlights
Harjot Gill, CEO, CodeRabbit
Edward Wu, Founder & CEO, Dropzone
Patrick Thompson, Co-founder & CEO, Clarify
4:05 p.m.
Panel: Interfacing with Reasoning Applications and Agents
Hassaan Raza, Co-founder & CEO, Tavus
Kiana Ehsani, Co-founder & CEO, Vercept
Shaun VanWeelden, Managing Director, Mercor
Moderated by Sabrina Albert (Wu), Partner, Madrona  
4:30 p.m.
Fireside Chat: Shaping the Next Generation of AI Reasoning
Jay Parikh, Executive Vice President, CoreAI, Microsoft
Soma Somasegar, Managing Director, Madrona
5 p.m.
Cocktails & Reception

2025 Speakers

Summit Agenda

Morning Sessions
8:00 – 8:20am
Networking Breakfast
8:20 – 8:30am
Introduction to Intelligent Applications | Matt McIlwain/Madrona
8:30 – 9:15am
Fireside chat | Data is the Driver | Matt Garman/AWS & Matt McIlwain/Madrona
9:15 – 10:00am
Intelligent Application Company Spotlights | WhyLabs, SeekOut, Cresta
10:00 – 10:30am
Break & Networking
10:30 – 10:50am
Keynote | Peter Lee/Microsoft
10:50 – 11:30am
Enablers Panel | What Enables Application Intelligence | Justin Borgman/Starburst, Anu Sharma/Statsig, and Alex Ratner/Snorkel | Moderated by Peter Lee
11:30 - 12:00pm
Lunch Break & Networking
Afternoon Sessions
2:00 – 12:40pm
Fireside chat | Emerging Trends that Matter in AI & ML (Foundation Models, Transformers, and Stable Diffusion) | Oren Etzioni/AI2 and Carlos Guestrin/Stanford | Moderated by Luis Ceze/OctoML
12:45 – 1:30pm
Breakout Sessions
Session A
Intersections of Life Sciences and Innovation | Maddison Maseli/Deepcell, Lucas Nivon/Cyrus Biotechnology, and Jonathan Carlson/Microsoft | Moderated by Charlotte Hubbert/Nanostring
Session B
Applying AI/ML in Robotics | Leo Dirac/Groundlight.ai, UW Professor/Siddhartha Srinivasa, Amanda Marrs/AMP Robotics | Moderated by Tim Porter/MadronaSession C: Sales Enablement | Craig Hanson/Gong, Prasad Raje/Outreach, Kyle Coleman/Clari | Moderated by Zoe Hillenmeyer/Peak.ai
1:30 – 1:45pm
Break
1:45 – 2:45pm
Keynote | Why we believe the next generation of applications will be intelligent | Charles Lamanna/Microsoft
2:45  – 3:05pm
Fireside chat | Intersections of ML & Life Sciences Applied in Healthcare | Yinhan Liu /Birch AI and Jon Turow/Madrona
3:05  – 3:35pm
Keynote | Intersections of Biology and Technology | Geoff von Maltzahn/Flagship Pioneering
3:35 – 3:45pm
Announce 2022 IA40 winners & PitchBook partnership | Sabrina Wu/ Madrona and Dan Cook/Pitchbook
3:45 – 4:15pm
IA40 2022 Winner Spotlights | Luis Ceze/OctoML and Cristóbal Valenzuela/RunwayML
4:15 – 4:30pm
Closing Remarks | Matt McIlwain/Madrona
4:30 – 5:30pm
Cocktails/Networking
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